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. 2021 May 8;296:100761. doi: 10.1016/j.jbc.2021.100761

Figure 3.

Figure 3

Proteolytic activity of DPPIII on peptides identified in the plasma of diabetic mice.A–C, Peptide 1 (A), Peptide 2 (B), or Peptide 3 (C) was incubated with DPPIII for the indicated times, and the cleaved products were analyzed by reversed-phase liquid chromatography. Arrows: Peptide 1 (A), Peptide 2 (B), or Peptide 3 (C); arrowheads: cleaved products; ∗: nonspecific contaminant. D, plasma Peptide 2 concentration in the mice of each group was determined by SRM. One-way ANOVA was used to compare the data of each group. ∗∗p < 0.01 versus C57BL/6 mice; §§p < 0.01 versus PBS-infused db/db mice.