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. 2021 Jun 1;35(4):543–554. doi: 10.1007/s00540-021-02948-2

Table 2.

The impact of ventilator and FRE changes on the MPVC setup

Action PS effect PH effect
Increase ventilator pressure control (PC) Decrease EtCO2 Decrease EtCO2
Decrease ventilator PC Increase EtCO2 Increase EtCO2
Increase ventilator positive end expiratory pressure (PEEP) Minimal increase EtCO2 Minimal increase ETCO2
Decrease ventilator PEEP Minimal decrease EtCO2 Minimal decrease EtCO2
Decrease PH’s FRE resistance No effect Decrease EtCO2
Increase PHs FRE resistance No effect Increase EtCO2
Increase ventilator I-time Decrease EtCO2 Decrease EtCO2
Decrease ventilator I-time Increase EtCO2 Increase EtCO2

For the standard MPVC setup, PS has the proximal line attached to give feedback to the ventilator (I.e., the three-way flow valve is turned to monitor PS). Each patient has their own FRE; however, adjusting the PS’s FRE has no effect since the proximal line is monitoring that patient. Thus, the FRE on the PH circuit is the only FRE that should be adjusted unless the patient’s lung compliances are switched