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. 2021 Apr 1;7(2):38. doi: 10.3390/gels7020038

Figure 2.

Figure 2

Schematic representation of the entire process involved in forming injectable cryogels. The methacrylate derivatives of HA (HAGM) and/or gelatin (MA-gelatin) are dissolved in water containing an initiator system. Then, it is frozen at three different temperatures: −20, −50 and −80 °C. Cryogelation occurs around the ice crystals. Interconnected spaces are obtained after melting at room temperature. Ultimately, macroporous cryogels can be injected successfully with a syringe through a 16 G hypodermic needle. [51].