Table 1.
Composition of WHO prequalified inactivated OCVs.
| Dukoral™ | Shanchol™, Euvichol™ | Quantity per Dose |
|---|---|---|
|
V. cholerae O1 Inaba classical strain Cairo 48 Heat inactivated |
Same as in Dukoral | 300 EU* LPS (~2.5 × 1010 bacteria) |
|
V. cholerae O1 Ogawa classical strain Cairo 50 Heat inactivated |
Same as in Dukoral | 300 EU of LPS (~2.5 × 1010 bacteria) |
|
V. cholerae O1 Ogawa classical strain Cairo 50 Formalin inactivated |
Same as in Dukoral | 300 EU of LPS (~2.5 × 1010 bacteria) |
|
V. cholerae O1 Inaba E1 Tor strain Phil 6973 Formalin inactivated |
Same as in Dukoral | 600 EU of LPS (~5 × 1010 bacteria) |
| — |
V. cholerae O139 strain 4260B Formalin inactivated |
600 EU of LPS (~5 × 1010 bacteria) |
| Cholera toxin B subunit (rCTB) | — | 1 mg |
*EU stands for ELISA units, referring to the capacity of the vaccine to bind specific anti-LPS antibody in an internationally used Inhibition-ELISA method for quantification of LPS antigen.