Table 4.

Comparison of the proportion of children with visual impairment by gestational age and other clinical characteristics ^a.

	Visual Impairment n (%)	p-Value
Full-term versus preterm
Preterm (gestational age <37 week)	6/19 (31.6)	0.56
Full-term (gestational age ≥37 weeks)	13/53 (24.5)
Structural eye abnormalities
With	0/2 (0.0)	1.0
Without	19/70 (27.1)
Microcephaly
With	1/5 (20.0)	1.0
Without	18/67 (26.9)
At risk for developmental delay b
With	5/16 (31.3)	0.75
Without	14/56 (25.0)
Other neurodevelopmental abnormalities c
With	2/4 (50.0)	0.28
Without	17/68 (25.0)
Confirmed ZIKV infection d
With	5/13 (38.5)	0.31
Without	14/59 (23.7)

^a Among 81 children meeting the United States Zika Pregnancy and Infant Registry (USZPIR) eligibility criteria who attended the Zika Health Brigade and charts could be located. USZPIR eligibility criteria included children born between 1 December 2015 and 31 March 2018 in the United States Virgin Islands, to mothers with confirmed or possible recent zika virus (ZIKV) infection as defined by (1) recent ZIKV infection detected by Zika ribonucleic acid nucleic acid amplification test (NAAT) on any maternal, placental, fetal, or infant specimen or (2) recent ZIKV or flavivirus infection detected by serologic tests of maternal, fetal, or infant specimen [14]. ^b At risk for developmental delay defined as delay in fine motor, communication, gross motor, problem solving, personal-social, and/or social-emotional domains based on results of screening using the Ages and Stages Questionnaire −3. ^c Other neurodevelopmental abnormalities included abnormal tone and/or movement, seizures, and arthrogryposis based on physical examination by a pediatric neurologist. ^d Confirmed ZIKV infection was defined as either: (1) positive NAAT or 2) positive or equivocal Zika Immunoglobulin M testing and ZIKV plaque reduction neutralization test (PRNT) ≥ 10 and dengue PRNT < 10.