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. 2021 May 18;12:624725. doi: 10.3389/fimmu.2021.624725

Figure 4.

Figure 4

MiRNA affects tumor progression by regulating MDSC. MiRNA is involved in regulating the differentiation, accumulation and function of MDSC. These miRNAs can be derived from MDSC itself. Furthermore, it’s also generated by tumor cells and transported to MDSC through exosomes to exert function. These regulatory effects ultimately affect tumor cell proliferation, metastasis, invasion, and vascular proliferation.