Table 3.

MiRNA related with MDSC in tumor progression.

MiRNA	Status	Target	MiRNA’s regulating in MDSC	Impact on tumor progression
MiR-30a	Upregulated	SOCS3	Increase differentiation and immunosuppressive function	Facilitate tumor growth of B-cell lymphoma (93)
MiR-494	Upregulated	PTEN	Enhance accumulation and functions	Promote tumor invasion and metastasis by upregulating MMPs (98)
MiR-155 MiR-21	Upregulated	SHIP-1 PTEN	Boost expansion	Accelerate tumor growth (101)
MiR-155	Downregulated	HIF-1α	Enhance the recruitment and functions	Promote tumor growth and angiogenesis (96)
MiR-486	Upregulated	Cebpa	Promote proliferation and inhibit apoptosis	(94)
MiR-223	Downregulated	MEF2C	Suppress differentiation	Reduce tumor growth (97)
MiR-200c	Upregulated	PTEN FOG2	Promote suppressive potential	Promote tumor growth (102)
MiR-17-5p MiR-20a	Downregulated	STAT3	Alleviate the suppressive function	Reduce tumor growth (103)
MiR-9	Upregulated	Runx1	Inhibit the differentiation and enhance function	Promote tumor growth (95)
MiR-9 MiR-181a	Upregulated	SOCS3 PIAS3	Promote early-stage development	Promote tumor growth and immune escape (91)
MiR-126a	Upregulated	S100A8/A9	Promote expansion	Promote tumor angiogenesis and lung metastasis (100)
MiR-29a MiR-92a	Upregulated	Hbp1 Prkar1a	Enhance the proliferation and function	(104)
MiR-107	Upregulated	DICER1 PTEN	Induce the expansion and activation	Facilitate invasion and metastasis (92)