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. 2021 May 27;13(5):406–418. doi: 10.4240/wjgs.v13.i5.406

Figure 5.

Figure 5

Pancreatic ductal adenocarcinoma. A: The ducts show features of malignancy including cytologic atypia and incomplete gland formation with loss of lobular architecture, in a prominent desmoplastic stroma (hematoxylin & eosin, 130 ×, scale 250 µm); B: SMAD4 immunostaining shows loss of SMAD4 expression in the malignant glands (SMAD4, 120 ×, scale 250 µm).