Table 2.

Univariate and multivariate Cox regression analyses for OS in our TMA cohort. AFP, alpha‐fetoprotein; ALB, albumin; ALT, alanine aminotransferase; AST, aspartate transaminase; CI, confidence interval; HBsAg, hepatitis B surface antigen; SNRPC, expression in tumor nucleus; TBIL, total bilirubin.

Variables	Univariate analysis			Multivariate analysis
	HR	95% CI	P value	HR	95% CI	P value
SNRPC (high : low)	2.792	1.791–4.350	<0.001*	2.103	1.324–3.340	0.002*
Age (≤51 : >51 years)	0.977	0.635–1.502	0.915
Sex (male : female)	2.834	1.037–7.741	0.042*	3.212	1.159–8.902	0.025*
HBsAg (positive : negative)	0.768	0.397–1.488	0.434
ALB (≤35 : >35 g L−1)	1.412	0.651–3.063	0.383
TBIL (>17.1 : ≤17.1 μmol L−1)	1.157	0.710–1.883	0.559
ALT (>40 : ≤40 U L−1)	1.429	0.927–2.201	0.106
AST (>45 : ≤45 U L−1)	1.995	1.292–3.081	0.002*	1.857	1.192–2.894	0.006*
AFP (>400 : ≤400 ng mL−1)	1.063	0.676–1.671	0.792
Tumor number (multiple : solitary)	2.742	1.729–4.349	<0.001*	2.091	1.290–3.389	0.003*
Tumor size (>5 : ≤5 cm)	1.448	0.939–2.232	0.094
Tumor encapsulation (incomplete : complete)	1.108	0.705–1.740	0.657
Vascular invasion (yes : no)	2.485	1.611–3.835	<0.001*	2.451	1.575–3.814	<0.001*
Cirrhosis (yes : no)	0.897	0.578–1.392	0.628
TNM stage (III : I–II)	2.997	1.939–4.632	<0.001*	1.331	0.567–3.127	0.511

^* P < 0.05.