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. 2021 May 24;11(6):1785–1798. doi: 10.1002/2211-5463.13160

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© 2021 The Authors. FEBS Open Bio published by John Wiley & Sons Ltd on behalf of Federation of European Biochemical Societies.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Fig. 5 — GESA of ZHX2 from TCGA GC samples. (A) Heat map of the top 50 features for each phenotype in high‐ and low‐ ZHX2 groups. (B–F) The five notable Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways (https://www.genome.jp/kegg) in the high ZHX2 expression group. (B) T cell receptor signaling pathway. (C) B cell receptor signaling pathway. (D) JAK‐STAT signaling pathway. (E) Chemokine signaling pathway. (F) Pathways in cancer. (G–K) The five notable KEGG pathways in the low ZHX2 expression group. (G) Ribosomes. (H) Peroxisomes. (I) DNA replication. (J) Proteasomes. (K) Oxidative phosphorylation.