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. Author manuscript; available in PMC: 2021 Jun 1.
Published in final edited form as: Nat Protoc. 2021 Jan 11;16(2):754–774. doi: 10.1038/s41596-020-00432-x

Fig. 1 ∣. Cells confined to narrow ranges of traditional morphological parameters still exhibit highly variable shapes.

Fig. 1 ∣

Scatter plot showing the distributions of 37,750 mouse embryonic fibroblast cells confined to a 3D axis of aspect ratio, shape factor, and solidity. The subset of 10 cells highlighted in red display substantial morphological heterogeneity, despite highly similar values of aspect ratio, circularity, and solidity.