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a, Images of phalloidin-stained (top) wild-type (LMNA+/+, left) and lamin-deficient (LMNA−/−, right) mouse embryonic fibroblasts. Segmentation is obtained using CellProfiler. Scale bar, 100 μm. b, Bar plots showing the distribution of cell shape modes from the VAMPIRE analysis of the MEFs. Numbers above the bars represent the abundances (%) of cells in each shape mode.
