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. 2021 Jun 1;153(8):e202012855. doi: 10.1085/jgp.202012855

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© 2021 Rook et al.

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Figure 5. — Q277N recovers nearly as fast as Q277G.(A) Outside-out patch recordings of cASIC1 Q277N recovery from desensitization with interpulse pH values of 8.0, 7.4, and 7.0 (upper, middle, and lower traces, respectively). All data are from the same patch. Note the break and change in time base between conditioning and test pulses. (B) Summary recovery curves (left) and time constants (right) for Q277N and Q277L recovery at different interpulse pH values. All pH values tested in the same patch. Symbols denote individual patches and error bars show SEM. (C) Summary of recovery time constants at various pH values for WT, Q277G, Q277N, and Q277L. WT data drawn from Rook et al., 2020a.