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. 2021 May 27;27:e929027-1–e929027-12. doi: 10.12659/MSM.929027

Figure 4.

Figure 4

Statistical graph of the expression of β-CaMKII/NMDAR/BDNF mRNA in the hippocampus of rats. (A) Expression of BDNF and β-CaMKII mRNA in the hippocampus by reverse transcription polymerase chain reaction (RT-PCR). (B) Expression of NMDAR mRNA in the hippocampus by RT-PCR. (C) Analysis of BDNF mRNA. (D) Analysis of β-CaMKII mRNA. (E) Analysis of NMDAR mRNA. Compared with the control (Con) group, * P<0.05, ** P<0.01, *** P<0.001; compared with the chronic unpredictable mild stress (CUMS) group, # P<0.05, ## P<0.01, ### P<0.001. Data represent mean±standard error of the mean. AP – acupuncture; BDNF – brain-derived neurotrophic factor; β-CaMKII – β isoform of calcium/calmodulin-dependent protein kinase II; Fx – fluoxetine; NMDAR – N-methyl-d-aspartate receptor.