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Binding mode of compound 47 to BCL6BTB (PDB ID: 6EW8). (A) Overall view of the packing of one BCL6BTB dimer (green and white) on top of a second BCL6BTB dimer (orange and purple) via inhibitor 47. The surface area of the neighboring BCL6BTB dimer that was interact with inhibitor 47 (yellow) was highlighted. (B) Detailed binding mode of inhibitor 47 to the neighboring BCL6BTB dimer. Key residues involved in the interactions were shown in sticks.
