Table 3.
Survival and strain data by abnormal LV strain.
| LV GLS ≤ −13.8 (“New normal”) N = 21 |
LV GLS > −13.8 (“New abnormal”) N = 27 |
P value | ||
|---|---|---|---|---|
| Survival (n, %) | 0.022a | |||
| Died | 2 (10%) | 11 (41%) | ||
| Survived | 19 (90%) | 16 (59%) | ||
| Length of stay | 27.19 ± 21.25 | 24.37 ± 25.68 | 0.686 | |
| ICU days | 15.76 ± 19.83 | 12.81 ± 23.72 | 0.649 | |
| Ventilator days | 14.43 ± 20.16 | 11.22 ± 17.90 | 0.616 | |
| Use of vasopressors | 6 (35%) | 13 (42%) | 0.762a | |
| Vital signs at time of TTE (mean ± SD) | ||||
| Systolic blood pressure | 121 ± 5 | 126 ± 4 | 0.469 | |
| Diastolic blood pressure | 71 ± 3 | 73 ± 3 | 0.635 | |
| Heart rate | 83 ± 3 | 83 ± 3 | 0.953 | |
| Troponinemia ≥ 0.01 at time of TTE (n, %) | 0.040a | |||
| Yes | 13 (62%) | 24 (89%) | ||
| No | 8 (38%) | 3 (11%) | ||
| Biomarkers (mean ± SD) | ||||
| Peak Troponin T | 0.07 ± 0.22 | 0.46 ± 0.99 | 0.086 | |
| Peak NT-proBNP | 5287 ± 11,416 | 10,289 ± 18,042 | 0.282 | |
| Peak Creatinine | 1.53 ± 1.18 | 3.37 ± 3.23 | 0.017 | |
| Echocardiographic data | ||||
| LV (mean ± SD) | EF | 63 ± 5 | 51 ± 17 | 0.003 |
| GCS | −30.48 ± 5.03 | −24.34 ± 7.22 | 0.002 | |
| RV (mean ± SD) | GLS | −17.76 ± 5.32 | −12.00 ± 4.50 | <0.001 |
| FWS | −19.58 ± 6.65 | −13.70 ± 5.90 | 0.003 | |
| FAC | 39.36 ± 10.64 | 32.69 ± 11.48 | 0.052 | |
a
Fisher's exact test, TTE = transthoracic echocardiogram, NT-proBNP = N-terminal pro brain natriuretic peptide, LV = left ventricle, RV = right ventricle, EF = ejection fraction, GCS = global circumferential strain, GLS = global longitudinal strain, FAC = fractional area change, FWS = free wall strain.