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. Author manuscript; available in PMC: 2021 Jun 1.
Published in final edited form as: Chem Biol Drug Des. 2021 Jan 26;97(5):1059–1078. doi: 10.1111/cbdd.13826

FIGURE 2.

FIGURE 2

N-acetyl cysteine conjugate 13 releases ITC-ARi 12b in aqueous solution. 13 (50 μM) was dissolved in PBS buffer (pH 7.4, 5% acetonitrile) and incubated at 37°C. Aliquots (10 μl) were taken at indicated time points and analyzed using high-performance liquid chromatography