FIGURE 2.

Regression coefficients (B) and 95% confidence intervals (95% CI) of cross-sectional linear regression analyses of log2-transformed biomarker concentrations with aspects of health-related quality of life 6 months after colorectal cancer diagnosis. Analyses were adjusted for sex, age, cohort (COLON, EnCoRe, ColoCare), neo-adjuvant therapy (yes/no), adjuvant therapy (yes/no), cancer stage (I, II, III), any supplement use (yes/no), total energy intake (kcal/day), alcohol intake (gr/day), BMI (kg/m²), adherence to physical activity guidelines (yes/no), creatinine (µmol/L), and cotinine (nmol/L). *Statistically significant after FDR adjustment for multiple testing. Abbreviations: COLON, COlorectal cancer: Longitudinal, Observational study on Nutritional and lifestyle factors that influence colorectal tumour recurrence, survival and quality of life; EnCoRe, Energy for life after ColoRectal cancer; FDR, false discovery rate; HKr, hydroxykynurenine ratio; QoL, quality of life.