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. 2021 Mar 1;113(6):1468–1481. doi: 10.1093/ajcn/nqaa422

FIGURE 3.

FIGURE 3

Regression coefficients (B) and 95% confidence intervals (95% CI) of linear regression analyses of standardized changes in biomarker concentrations (concentration at 6 months − concentration at diagnosis) with aspects of health-related quality of life 6 months after colorectal cancer diagnosis. Analyses were adjusted for sex, age, cohort (COLON, EnCoRe, ColoCare), neo-adjuvant therapy (yes/no), adjuvant therapy (yes/no), cancer stage (I, II, III), any supplement use (yes/no), biomarker concentration at diagnosis, total energy intake (kcal/day), alcohol intake (gr/day), BMI (kg/m2), adherence to physical activity guidelines (yes/no), creatinine (µmol/L), and cotinine (nmol/L). Abbreviations: COLON, COlorectal cancer: Longitudinal, Observational study on Nutritional and lifestyle factors that influence colorectal tumour recurrence, survival and quality of life; EnCoRe, Energy for life after ColoRectal cancer; FDR, false discovery rate; HKr, hydroxykynurenine ratio; QoL, quality of life.