Table 4.
Brain activation during reading and word learning: Main fMRI results from the controls. All peak values reported were significant at p < .001 (uncorrected) at voxel level, 10 voxels spatial extent. Peak coordinates of each cluster are reported in MNI coordinates.
| Side | Cluster size (voxels) | t value | Peak coordinate |
|||
|---|---|---|---|---|---|---|
| x | y | Z | ||||
| Reading task | ||||||
| (Word + pseudoword)versus false-font | ||||||
| MOG* | R | 998 | 21.60 | 20 | −92 | −6 |
| MOG/LG* | L | 1660 | 21.20 | −24 | −86 | 14 |
| PG/MFG* | L | 14 | 7.77 | −50 | 14 | 46 |
| PG/MFG* | R | 64 | 7.50 | 54 | 2 | 44 |
| SPL* | L | 30 | 7.40 | −26 | −54 | 46 |
| Word learning task | ||||||
| Novel word–picture pairs versus rest (whole brain) | ||||||
| L FG/R MOG/L MOG* | L | 7825 | 38.54 | −42 | −66 | −14 |
| L | 27.83 | −26 | −84 | 16 | ||
| R | 25.79 | 36 | −78 | −16 | ||
| PG/MFG* | L | 146 | 16.25 | −50 | 0 | 40 |
| IFO* | L | 30 | 12.55 | −40 | 48 | −16 |
| PG/MFG* | R | 146 | 10.05 | 38 | 8 | 62 |
| FG* | L | 119 | 8.35 | −34 | −36 | −26 |
| MFO* | R | 22 | 8.13 | 24 | 46 | −20 |
| SPL* | L | 45 | 7.13 | −36 | −52 | 50 |
| Novel word–picture pairs versus rest (hippocampal ROI) | ||||||
| Hippocampus* | L | 10 | 8.79 | −18 | −28 | −6 |
| Hippocampus* | L | 13 | 7.20 | −30 | −20 | −14 |
| Hippocampus* | R | 14 | 6.93 | 26 | −34 | 2 |
FDR-Corrected at peak level (p < .05); PG, Precentral Gyrus; MOG, Middle Occipital Gyrus; MFG, Middle Frontal Gyrus; LG Lingual Gyrus; SPL, Superior Parietal Lobe; IFO Inferior Fronto-Orbital Gyrus. FG, Fusiform Gyrus; MFO Middle Fronto-Orbital Gyrus.