Table 5.
Direct contrasts between the controls and AA on the reading and learning task. All peak values reported were significant at p < .001 (uncorrected) at voxel level, 10 voxels spatial extent except for the comparison between AA > Controls for the Learning task. The latter is reported at p < .01, since no significant voxels were found at p < .001 with 10 voxels spatial extent. Peak coordinates of each cluster are reported in MNI coordinates.
Side | Cluster size (mm3) | t value | Peak coordinate |
|||
---|---|---|---|---|---|---|
x | y | z | ||||
Reading task | ||||||
(Word + pseudoword) versus false-font | ||||||
Controls > patient AA | ||||||
MTG | L | 17 | 6.44 | −52 | −40 | 2 |
LG | L | 44 | 8.52 | −12 | −68 | 6 |
Patient AA > Controls | ||||||
SFG* | L | 80 | 10.46 | −14 | 30 | 54 |
MTG* | R | 187 | 9.17 | 68 | −40 | 0 |
ANG | R | 20 | 8.52 | 56 | −54 | 24 |
Word learning task | ||||||
Novel word–picture pairs versus rest (whole brain) | ||||||
Controls > patient AA | ||||||
MFG* | R | 84 | 18.24 | 46 | 48 | 6 |
STG | L | 48 | 12.03 | −46 | −4 | 0 |
Hippocampus | R | 74 | 10.95 | 22 | −18 | −14 |
HG/STG | R | 44 | 9.24 | 42 | −22 | 14 |
Insula | R | 64 | 8.51 | 40 | 20 | −6 |
Patient AA > Controls (p < .01) | ||||||
FG/ITG | R | 67 | 6.92 | 30 | −4 | −42 |
Hippocampus | L | 29 | 6.42 | −32 | −32 | 10 |
MTG | L | 62 | 5.93 | −52 | −64 | −2 |
MTG | R | 33 | 4.37 | 54 | −48 | 0 |
FDR-Corrected at peak level (p < .05); SFG, Superior Frontal Gyrus; MTG, Middle Temporal Gyrus; STG, Superior Temporal Gyrus; ANG, Angular Gyrus; LG, Lingual Gyrus; MFG, Middle Frontal Gyrus; HG, Heschl Gyrus; ITG Inferior Temporal Gyrus. FG, Fusiform Gyrus.