Table 3D.
Datasets | Category | Treg source | Type | Total DEG | Casp-1up | /DEG% | Casp-1down | /DEG% | Casp-4 up | /DEG% | Casp-4 down | /DEG% |
---|---|---|---|---|---|---|---|---|---|---|---|---|
GSE119169 | Lymphoid | Spleen | Array | 44 | 0 | 0.00 | 0 | 0.00 | 2 | 4.55 | 0 | 0.00 |
GSE37532 | Lymphoid | Lymph node | Array | 397 | 8 | 2.02 | 0 | 0.00 | 12 | 3.02 | 0 | 0.00 |
E-MTAB-7961 | Lymphoid | Spleen | RNA-seq | 1802 | 15 | 0.83 | 3 | 0.17 | 35 | 1.94 | 9 | 0.50 |
GSE20366 | Non-lymphoid | Small intestinal lamina propria | Array | 756 | 16 | 2.12 | 11 | 1.46 | 15 | 1.98 | 11 | 1.46 |
GSE64909 | Non-lymphoid | Brown adipose tissue | Array | 113 | 8 | 7.08 | 0 | 0.00 | 8 | 7.08 | 0 | 0.00 |
GSE37532 | Non-lymphoid | Visceral adipose tissue(VAT) | Array | 924 | 18 | 1.95 | 2 | 0.22 | 22 | 2.38 | 5 | 0.54 |
E-MTAB-7961 | Non-lymphoid | Kidney | RNA-seq | 1584 | 20 | 1.26 | 4 | 0.25 | 42 | 2.65 | 5 | 0.32 |
GSE50096 | Lymphoid | Skeletal muscle injured 2w spleen | Array | 308 | 6 | 1.95 | 0 | 0.00 | 10 | 3.25 | 1 | 0.32 |
GSE50096 | Lymphoid | Skeletal muscle injured 4d spleen | Array | 313 | 7 | 2.24 | 0 | 0.00 | 13 | 4.15 | 1 | 0.32 |
E-MTAB-7961 | Non-lymphoid | Fibrosis kidney | RNA-seq | 2440 | 13 | 0.83 | 4 | 0.25 | 37 | 2.36 | 8 | 0.51 |
E-MTAB-7961 | Non-lymphoid | Regeneration kidney | RNA-seq | 2365 | 25 | 1.06 | 6 | 0.25 | 56 | 2.37 | 7 | 0.30 |
GSE50096 | Non-lymphoid | Skeletal muscle injured 2w muscle | Array | 539 | 10 | 1.86 | 0 | 0.00 | 11 | 2.04 | 5 | 0.93 |
GSE50096 | Non-lymphoid | Skeletal muscle injured 4d muscle | Array | 465 | 10 | 2.15 | 2 | 0.43 | 10 | 2.15 | 8 | 1.72 |
GSE116347 | Lymphoid | Tumor bearing mouse (B16) spleen | RNA-seq | 1218 | 20 | 1.64 | 3 | 0.25 | 35 | 2.87 | 3 | 0.25 |
GSE116347 | Lymphoid | Tumor bearing mouse (MC38) spleen | RNA-seq | 1298 | 18 | 1.39 | 2 | 0.15 | 42 | 3.24 | 4 | 0.31 |
GSE116347 | Lymphoid | Tumor bearing mouse (CT26) spleen | RNA-seq | 905 | 14 | 1.55 | 1 | 0.11 | 28 | 3.09 | 2 | 0.22 |
GSE120280 | Lymphoid | Tumor bearing mouse (TC-1) spleen | RNA-seq | 1776 | 21 | 1.18 | 9 | 0.51 | 38 | 2.14 | 11 | 0.62 |
GSE139372 | Non-lymphoid | Melanoma Skin | RNA-seq | 1571 | 2 | 0.13 | 8 | 0.51 | 8 | 0.51 | 19 | 1.21 |
GSE120280 | Non-lymphoid | Tumor bearing mouse (TC-1) tumor | RNA-seq | 1933 | 18 | 0.93 | 6 | 0.31 | 33 | 1.71 | 13 | 0.67 |
GSE89225 | Non-lymphoid | Breast Tumor | RNA-seq | 1493 | 9 | 0.60 | 6 | 0.40 | 16 | 1.07 | 18 | 1.21 |
GSE116347 | Non-lymphoid | Tumor bearing mouse (B16) tumor | RNA-seq | 2462 | 42 | 1.71 | 9 | 0.37 | 72 | 2.92 | 23 | 0.93 |
GSE116347 | Non-lymphoid | Tumor bearing mouse (MC38) tumor | RNA-seq | 1651 | 27 | 1.64 | 11 | 0.67 | 39 | 2.36 | 21 | 1.27 |
GSE116347 | Non-lymphoid | Tumor bearing mouse (CT26) tumor | RNA-seq | 1393 | 9 | 0.65 | 16 | 1.15 | 11 | 0.79 | 52 | 3.73 |
GSDMD, Gasdermin-D; Casp-1, caspase-1; Casp-4, caspase-4; DEG, differentially expressed gene.
However, the total numbers in each Treg datasets was too low to perform IPA analysis. The detailed lists were shown in Supplementary Table 7 .