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. 2020 May 15;106(6):1714–1724. doi: 10.3324/haematol.2019.245860

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Figure 5. — CA9 accelerates breast implant-associated anaplastic large cell lymphoma growth in a mouse xenograft model. (A) Mice inoculated with TLBR-3 breast implant-associated anaplastic large cell lymphoma cells stably transduced with a CA9 lentiviral vector develop palpable tumors faster than mice inoculated with cells transduced with vector control. (B) Mice inoculated with TLBR-3 cells overexpressing CA9 develop larger tumors than mice inoculated with control-transduced TLBR-3 cells. (C) Overall survival is shorter in mice bearing CA9-overexpressing TLBR-3 tumors than in those bearing control-transduced tumors.