Table 1.

Summary of mechanisms of epigenetic regulation and examples of key targets within each class

Class of epigenetic regulators	Example of key targets
DNA methyltransferases	DNMT1, DNMT3, DNMT3a, DNMT3b
Histone lysine methyltransferases (KMTs)	EZH1/2, SETD2, SMYD3
Histone lysine demethylases (KDMs)	LSD1, KDM2, KDM3A
Histone arginine methyltransferases	PRMT1, PRMT4, PRMT6
Histone arginine demethylases	JMJD6
Histone acetyltransferases (HATs)	CREBBP/EP300, CBP, CAT6B
Histone deacetylases (HDACs)	HDAC1, HDAC3, HDAC6, HDAC7
Histone readers	BRD2/3/4, YEATS2
MicroRNA (miRNA)	Let-7, miR-200
Long noncoding RNA (lncRNA)	MALAT1, HOTAIR
Circular RNA (circRNA)	CDR1as, circ-FOXO3
Small nucleolar RNA (snoRNA)	SNORA42. SNORA78