TABLE 4.

Relative hazards (HR) with 95% confidence intervals (CI) of kidney outcomes occurring 2–10 years post-HCT among allogeneic and autologous survivors^*

Outcome / risk factor	Allogeneic	Autologous
	HCT	HCT
	HR (95% CI)	HR (95% CI)
Acute kidney failure
Age at HCT‡	2.4 (1.5–3.7)	2.0 (1.3–2.9)
History of post-HCT relapse	2.8 (1.5–5.1)	2.1 (1.1–4.0)
History of hypertension	2.9 (1.7–5.0)	2.5 (1.3–4.7)
History of diabetes	1.0 (0.4–2.4)	3.8 (1.5–9.2)
History of cGVHD	1.4 (0.7–2.6)	n/a
Chronic kidney disease
Age at HCT‡	2.4 (1.3–4.3	1.8 (1.1–2.8)
History of post-HCT relapse	0.9 (0.3–2.9)	1.3 (0.5–3.5)
History of hypertension	5.2 (2.7–10.0)	4.8 (2.4–9.6)
History of diabetes	0.7 (0.2–2.3)	1.3 (0.3–5.6)
History of cGVHD	2.5 (0.9–7.2)	n/a

cGVHD, chronic graft vs. host disease; n/a, not applicable

^*Models adjusted for all risk factors listed plus sex, race/ethnicity, and year of HCT.

^‡Calculated in 20-year increments