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. 2021 May 31;36(1):964–976. doi: 10.1080/14756366.2021.1907575

Table 1.

Inhibition data of CA isoforms I, II, IX, and XII by inhibitors ACTZ, AN6-277, and AN11-740 by a stopped flow CO2 hydrase assay29.

Cmpd KI (nM)a
CA I CA II CA IX CA XII
ACTZ 250 ± 15 12 ± 0.8 25 ± 1.4 5.7 ± 0.5
AN6-277b 565.6 ± 34.2 1.2 ± 0.1 2.6 ± 0.2 1.1 ± 0.1
AN11-740 1580 ± 110c 5.9 ± 0.4 c 1.3 ± 0.1 3.0 ± 0.2

aInhibition data are expressed as means ± SEM of 3 different assays; bdata from ref25; cdata from ref26.