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. 2021 May 27;28(1):995–1006. doi: 10.1080/10717544.2021.1928794

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© 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Agarose gel retardation assay and cytotoxicity tests of the nanoparticles. (A) Electrophoretic bands of PSH-NP/S at various PSH/siRNA molar ratios from 12:1 to 2:1. (B) Electrophoretic bands of PEI-NP/S, PSH-NP/S, cRGD-NP/S and cRGD-PSH-NP/S. (C) Electrophoretic bands of naked siRNA and cRGD-PSH-NP/S after incubating with FBS for several time periods. (D) Cell viability of HepG-2 cells treated with PEI-NP, PSH-NP, cRGD-NP and cRGD-PSH-NP. (E) Cell viability of LO2 cells treated with PEI-NP, PSH-NP, cRGD-NP and cRGD-PSH-NP. Each bar is the mean of six experiments normalized to mean ± SD. (*p < .05 vs control; **p < .01 vs control).