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A) Forest plot of pooled incidence rate (patient-years) for MBC, irrespective of subtype. Random effects model presented. Incidence per year of follow-up ranged from 0.02 to 0.19. Median follow-up times ranged from 12.0 to 137.0 months. B) Funnel Plot for publication bias according to studies reporting brain metastasis in MBC, irrespective of subtype. Egger’s test, P = 0.88. MBC, metastatic breast cancer.
