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. 2021 Jun 1;16(6):e0251775. doi: 10.1371/journal.pone.0251775

Table 1. Haemodynamic and laboratory analyses of ISCLS patients admitted to ICU because of shock.

Variable Acute phase Post-acute phase Recovery phase p
Haemodynamics
HR, mean (range), bpm 125.7 (94.5–146.9) 96.8 (90–105)* 74 (67.7–85.8)* <0.001
SAP, mean (range), mmHg 75.4 (55–96.1) 109.2 (94.9–119.9)* 122.6 (102.7–149)* <0.001
DAP, mean (range), mmHg 50.7 (40–60.8) 70 (60.3–77.4)* 72.6 (56.3–90.5)* 0.008
Blood analysis
Hb, mean (range), g/dL 19.8 (12.1–24.7) 16.8 (9.8–20.1) 10.6 (7.7–13.4)*§ 0.002
Ht, mean (range), % 57.2 (35.3–72) 48.9 (27.9–57) 31.1 (23–40)*§ 0.002
RBC, mean (range), 103 cells/mm3 6815 (4090–7990) 5845 (3510–7070) 3675 (2750–4700)*§ 0.002
WBC, mean (range), cells/mm3 38878 (18520–66440) 23817 (6250–42470) 10300 (7520–13840)* 0.009
PLT, mean (range), 103 platelets/mm3 223.6 (164–294) 254.5 (159–353) 173.1 (94–336) 0.14
PTT, mean (range), INR 1.56 (0.97–2.36) 1.2 (0.9–1.6) 1.02 (0.77–1.15)* 0.03
PT, mean (range), INR 1.56 (1.19–2.16) 1.22 (1.1–1.44) 1.1 (1.04–1.2)* 0.08
D-dimer, mean (range), μg/L 1354 (503–3609) 1243 (789–1770) 827 (388–1065) 0.64
Urea, mean (range), mg/dL 86 (67–116) 144 (86–303) 99.8 (36–172) 0.3
Creatinine, mean (range), mg/dL 3.18 (2.2–4.3) 3.8 (1.9–5.7) 2.1 (1.03–4.3) 0.06
Albumin, mean (range), g/dL 1.9 (0.9–2.5) 2.8 (2.1–3.5) 3.2 (2.7–3.7)* 0.008
C-reactive protein, mean (range), mg/L 43 (7–88) 44.5 (17–111) 35.3 (8.9–67) 0.86
CPK, mean (range), U/L 285 (129–540) 1806 (118–9084) 113 (28–206) 0.1
Lactate, mean (range), mmol/L 4.2 (2.2–8.1) 1.8 (0.9–2.8) 0.8 (0.5–1)* 0.003

Haemodynamic data, blood sample analyses and acid-base status of patients admitted to ICU because of life-threatening ISCLS attacks. HR, heart rate; SAP, systolic arterial pressure; DAP, diastolic arterial pressure. Values are shown as mean (range).

*p<0.05 with respect to the acute phase.

§p<0.05 with respect to the post-acute phase.