Table 4.
Odds Ratio of uACR ≥ 30 mg/g by LAP Quartiles in Metabolic Stratified Groups with Prediabetes
| Variables | Odds Ratio (95%CI) of Increased uACR by LAPI LAPI Quartiles | P-value for Trend | P-value for Interaction | |||
|---|---|---|---|---|---|---|
| Q1 | Q2 | Q3 | Q4 | |||
| uACR ≥30 mg/g | ||||||
| BP, mmHg | 0.012 | |||||
| SBP <120 and DBP <80 | 1.00 | 1.15 (0.94–1.41) | 1.27 (1.02–1.57)* | 1.36 (1.06–1.74)* | 0.010 | |
| ≤120 SBP <140 and/or ≤80 DBP <90 |
1.00 | 1.02 (0.77–1.35) | 1.21 (0.92–1.60) | 1.45 (1.09–1.94)* | 0.048 | |
| SBP ≥140 or DBP ≥90 | 1.00 | 1.44 (0.97–2.13) | 1.29 (0.87–1.91) | 2.08 (1.40–3.09)* | 0.001 | |
| BMI, kg/m2 | 0.256 | |||||
| <18.5 | 1.00 | 0.87 (0.45–1.68) | 0.71 (0.26–1.94) | 0.70 (0.14–3.52) | 0.224 | |
| 18.5–23.9 | 1.00 | 0.99 (0.83–1.18) | 1.05 (0.87–1.27) | 1.10 (0.88–1.39) | 0.121 | |
| 24–27.9 | 1.00 | 2.15 (1.19–3.87)* | 1.89 (1.06–3.36)* | 2.34 (1.32–4.16)* | <0.001 | |
| ≥28 | 1.00 | 2.13 (0.48–9.41) | 1.79 (0.45–7.18) | 1.96 (0.50–7.68) | 0.463 | |
Notes: *Significance of P-value (P<0.05). Adjusted for age; sex; BMI; DM family; drinking; smoking; SBP; DBP; HDL; FBG; PBG; HbA1c.
Abbreviations: uACR, urinary albumin to creatinine ratio; LAPI, lipid accumulation product index; BMI, body mass index; DM, diabetes mellitus; CVD, cardiovascular disease; HDL, high-density lipoprotein cholesterol; FBG, fasting blood glucose; PBG, 2-h postload blood glucose; HbA1c, glycosylated hemoglobin.