Table 2.
Correlations of Fold Decreases Among circRNA-TBC1D4, circRNA-NAALAD2, circRNA-TGFBR3 and Clinical Features in 20 Patients
| CircRNA-TBC1D4 | CircRNA-NAALAD2 | CircRNA-TGFBR3 | Age | INSS Stage | Risk Group | FH/UH | MYCN Status | LDH | NSE | SF | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| CircRNA-TBC1D4 | / |
P < 0.0001 R = 0.9920 |
P = 0.0044 R = 0.7824 |
P = 0.8613 R = 0.0600 |
P = 0.1894 R = 0.4278 |
P = 0.0830 R = 0.5449 |
P = 0.0790 R = 0.6533 |
P = 0.0488 R = 0.6344 |
P = 0.0109 R = 0.7590 |
P = 0.3222 R = 0.3297 |
P = 0.4138 R = 0.2746 |
| CircRNA-NAALAD2 |
P < 0.0001 R = 0.9920 |
/ |
P = 0.0058 R = 0.7679 |
P = 0.8960 R = 0.0447 |
P = 0.1761 R = 0.4395 |
P = 0.0614 R = 0.5800 |
P = 0.0810 R = 0.6500 |
P = 0.0574 R = 0.6170 |
P = 0.0214 R = 0.7101 |
P = 0.3230 R = 0.3291 |
P = 0.5265 R = 0.2145 |
| CircRNA-TGFBR3 |
P = 0.0044 R = 0.7824 |
P = 0.0058 R = 0.7679 |
/ |
P = 0.4588 R = 0.2498 |
P = 0.6175 R = 0.1700 |
P = 0.3980 R = 0.2835 |
P = 0.0001 R = 0.9692 |
P = 0.0526 R = 0.6266 |
P = 0.1492 R = 0.4913 |
P = 0.5853 R = 0.1855 |
P = 0.8801 R = 0.0520 |
Notes: Continuous variables: fold decrease in circRNA-TBC1D4, circRNA-NAALAD2, and circRNA-TGFBR3, age, LDH, NSE and SF; categorical variables: INSS stage (I, II, IVs and III, IV), risk group (low, intermediate, high), FU/UH, MYCN status (amplified or not).
Abbreviations: INSS, International Neuroblastoma Staging System; FH, favorable histology group; UH, unfavorable histology group.