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. 2021 Mar-Apr;14(2):250–256. doi: 10.25122/jml-2019-0160

Table 1.

The frequency distribution of side effects and improvement of symptoms in the vulvovaginal candidiasis, bacterial vaginosis, and nonspecific vaginitis groups.

Groups Side effects Chlorhexidine vaginal gel Clotrimazole vaginal gel Oral metronidazole Combination therapy (oral metronidazole and clotrimazole vaginal gel)
Vulvovaginal candidiasis (N=34) Vaginal burning 14 (82.35%) 14 (82.35%) - -
Nausea 0 0 - -
Vomiting 0 0 - -
Cutaneous lesions 0 1 (5.88%) - -
Improvement 15 (88.23%) 16 (94.11%) - -
Bacterial vaginosis (N=41) Vaginal burning 10 (43.47%) - 2 (11.11%) -
Nausea 0 - 1 (5.55%) -
Vomiting 0 - 1 (5.55%) -
Cutaneous lesions 0 - 0 -
Improvement 23 (100%) - 18 (100%) -
Nonspecific vaginitis (N=36) Vaginal burning 5 (27.77%) - - 6 (33.33%)
Nausea 0 - - 0
Vomiting 0 - - 0
Cutaneous lesions 3 (16.66%) - - 0
Improvement 18 (100%) - - 18 (100%)