Table 1.
Baseline characteristics
| AVB cohorta, n (%) | General population cohortb, n (%) | P-value | |
|---|---|---|---|
| Total | 517 (100) | 5170 (100) | — |
| Male sex | 299 (57.8) | 2990 (57.8) | — |
| Median age | 41.3 (IQR 32.7–46.2) | 41.3 (IQR 32.7–46.2) | — |
| Age at baseline | |||
| 0–10 | 7 (1.6) | 70 (1.6) | — |
| 10–20 | 28 (5.4) | 280 (5.4) | — |
| 20–30 | 69 (13.3) | 690 (13.3) | — |
| 30–40 | 132 (25.5) | 1320 (25.5) | — |
| 40–50 | 281 (54.4) | 2810 (54.4) | — |
| Device type | |||
| Brady pacemaker | 513 (99.2) | — | — |
| Biventricular pacemaker | 4 (0.8) | — | — |
| LVEF | |||
| >50% | 351 (67.9) | — | — |
| 50–40% | 6 (1.2) | — | — |
| <40% | 4 (0.8) | — | — |
| Missing/older than 30 days | 156 (30.1) | — | — |
| Cardiovascular comorbidity | |||
| Congestive heart failure | 7 (1.4) | 4 (0.1) | <0.001 |
| Hypertension | 64 (12.4) | 300 (5.8) | <0.001 |
| Diabetes mellitus | 13 (2.5) | 86 (1.7) | 0.158 |
| Hypercholesterolaemia | 30 (5.8) | 138 (2.7) | <0.001 |
| Prior AMI | 7 (1.4) | 16 (0.3) | <0.001 |
| AF/AFL | 19 (3.7) | 13 (0.3) | <0.001 |
| Charlson comorbidity index | <0.001 | ||
| 0 | 421 (81.4) | 4793 (92.7) | — |
| 1 | 75 (14.5) | 339 (6.6) | — |
| 2–3 | 15 (2.9) | 25 (0.5) | — |
| 4+ | 6 (1.2) | 13 (0.2) | — |
AF, atrial fibrillation; AFL, atrial flutter; AMI, acute myocardial infarction; AVB, atrioventricular block; IQR, interquartile range; LVEF, left ventricular ejection fraction.
a
Patients <50 years when receiving their first pacemaker due to AVB.
b
Control cohort matched by age and gender.