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. 2021 May 12;12(11):1743–1751. doi: 10.1111/1759-7714.13989

TABLE 4.

Associations between CD8‐positive T cells and CD68‐positive macrophage density with PD‐L1 expression, CD47 expression, and PD‐L1/CD47 co‐expression in LUAD cases

Factors PD‐L1, N% CD47 PDL1/CD47
Positive Negative p Positive Negative p Positive Negative p
CD8 Low 15 108 0.008 84 39 0.254 12 111 0.043
High 30 87 88 29 23 94
CD68 Low 17 104 0.070 82 39 0.199 15 106 0.365
High 28 91 90 29 20 99

Abbreviations: CD8, cluster of differentiation 8; CD47, cluster of differentiation 47; CD68, cluster of differentiation 68; CI, confidence interval; HR hazard ratio; LUAD, lung adenocarcinoma; PD‐L1, programmed cell death‐ligand 1.