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. 2021 May 4;12(11):1708–1715. doi: 10.1111/1759-7714.13906

FIGURE 3.

FIGURE 3

Knockdown of Snail in H1975/OR. (a) The knockdown of snail was verified by Western blot in H1975OR si‐snail#1 and si‐snail#2. (b) E‐cadherin was upregulated, while N‐cadherin and vimentin were downregulated in H1975OR si‐snail#1. (c) The number of cells penetrating the transwell was reduced in H1975OR si‐snail#1. (d) Wound healing was slow in H1975/OR si‐snail#1. (e) IC 50 of osimertinib was 11.5 nM in H1975OR si‐snail#1 (f) mRNA of EMT gene in H1975, H1975/OR and H1975/OR si‐snail#1