Table 3.
Subgroup analyses by various exclusion for glycosylated hemoglobin, depression and stress
Outcome | No. studies | Pooled effect estimates | Heterogeneity | ||
---|---|---|---|---|---|
SMD (95% CI) | P‐value | I 2 | PQ | ||
Baseline HbA1c | |||||
HbA1c | |||||
<8% | 4 | –0.26 † (−0.47, −0.05) | 0.01 | 0% | 0.77 |
≥8% | 3 | –0.22 † (−0.57, 0.13) | 0.22 | 0% | 0.66 |
Depression | |||||
<8% | 3 | –0.67(−0.87, −0.46) | <0.00001 | 0% | 0.73 |
≥8% | 5 | –0.49(−0.98, −0.01) | 0.05 | 73% | 0.006 |
Stress | |||||
<8% | 5 | –0.55(−0.84, −0.27) | 0.0002 | 60% | 0.06 |
≥8% | 2 | –0.57(−1.17, 0.04) | 0.06 | 65% | 0.09 |
Baseline psychological status | |||||
HbA1c | |||||
Without psychological disorder | 5 | –0.30 † (−0.52, −0.08) | 0.007 | 0% | 0.86 |
With psychological disorder | 2 | –0.15 † (−0.46, 0.16) | 0.34 | 0% | 0.75 |
Depression | |||||
Without psychological disorder | 4 | –0.37(−0.85, −0.10) | 0.13 | 74% | 0.009 |
With psychological disorder | 4 | –0.72(−0.93, −0.51) | <0.00001 | 0% | 0.69 |
Stress | |||||
Without psychological disorder | 5 | –0.37(−0.60, −0.15) | 0.001 | 13% | 0.33 |
With psychological disorder | 2 | –0.79(−1.04, −0.55) | <0.00001 | 0% | 0.97 |
Duration of follow up | |||||
HbA1c | |||||
<6 months | 4 | –0.21 † (−0.48, 0.06) | 0.13 | 0% | 0.84 |
≥6 months | 3 | –0.28 † (−0.52, −0.04) | 0.006 | 0% | 0.60 |
Depression | |||||
<6 months | 6 | –0.53(−0.91, −0.15) | 0.006 | 69% | 0.007 |
≥6 months | 2 | –0.65(−0.90, −0.39) | <0.00001 | 0% | 0.45 |
Stress | |||||
<6 months | 4 | –0.58(−0.91, −0.26) | 0.0004 | 44% | 0.14 |
≥6 months | 3 | –0.47(−0.82, −0.12) | 0.009 | 62% | 0.07 |
Standardized mean difference was used for pooled effect estimates unless otherwise indicated.
Mean difference was used for pooled effect estimates. CI, confidence interval; HbA1c, glycosylated hemoglobin; SMD, standardized mean difference.