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. 2020 Nov 22;12(6):1092–1103. doi: 10.1111/jdi.13439

Table 3.

Subgroup analyses by various exclusion for glycosylated hemoglobin, depression and stress

Outcome No. studies Pooled effect estimates Heterogeneity
SMD (95% CI) P‐value I 2 PQ
Baseline HbA1c
HbA1c
<8% 4 –0.26 (−0.47, −0.05) 0.01 0% 0.77
≥8% 3 –0.22 (−0.57, 0.13) 0.22 0% 0.66
Depression
<8% 3 –0.67(−0.87, −0.46) <0.00001 0% 0.73
≥8% 5 –0.49(−0.98, −0.01) 0.05 73% 0.006
Stress
<8% 5 –0.55(−0.84, −0.27) 0.0002 60% 0.06
≥8% 2 –0.57(−1.17, 0.04) 0.06 65% 0.09
Baseline psychological status
HbA1c
Without psychological disorder 5 –0.30 (−0.52, −0.08) 0.007 0% 0.86
With psychological disorder 2 –0.15 (−0.46, 0.16) 0.34 0% 0.75
Depression
Without psychological disorder 4 –0.37(−0.85, −0.10) 0.13 74% 0.009
With psychological disorder 4 –0.72(−0.93, −0.51) <0.00001 0% 0.69
Stress
Without psychological disorder 5 –0.37(−0.60, −0.15) 0.001 13% 0.33
With psychological disorder 2 –0.79(−1.04, −0.55) <0.00001 0% 0.97
Duration of follow up
HbA1c
<6 months 4 –0.21 (−0.48, 0.06) 0.13 0% 0.84
≥6 months 3 –0.28 (−0.52, −0.04) 0.006 0% 0.60
Depression
<6 months 6 –0.53(−0.91, −0.15) 0.006 69% 0.007
≥6 months 2 –0.65(−0.90, −0.39) <0.00001 0% 0.45
Stress
<6 months 4 –0.58(−0.91, −0.26) 0.0004 44% 0.14
≥6 months 3 –0.47(−0.82, −0.12) 0.009 62% 0.07

Standardized mean difference was used for pooled effect estimates unless otherwise indicated.

Mean difference was used for pooled effect estimates. CI, confidence interval; HbA1c, glycosylated hemoglobin; SMD, standardized mean difference.

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