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Circulating tumor cells could improve the management of cancers in several ways. Using the prognostic value of the CTC count or of the CTC fluctuations could allow for the treatment intensification in patients with a poor prognosis or de‐escalation in patients with a good prognosis. It could also serve as an endpoint to evaluate the efficacy of a treatment. Molecular characteristics of CTCs could also be used for their theranostic value.
