Table 1.
Symbol | Parameter (dimension) | Default value (range*) |
ρ | Tumor growth rate (cells/day) | 1 (0–7) |
ξ | Relative killing rate (cells/day) | 0.001 (0–0.05) |
h | Michaelis constant (cells) | 571 |
δ | Death rate of immune cells (cells/day) | 0.01958 |
α | Conversion rate of naive T cells into specific T cells (cells/day) | 0.0025 |
pS | Total production rate of effector T cells from lymph nodes (cells/day) | 1 |
mS | Migration rate from lymph node to tumor microenvironment (cells/day) | 1 |
*If not fixed.
ODE, ordinary differential equation.