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. 2021 May 31;9(5):e002032. doi: 10.1136/jitc-2020-002032

Table 1.

Simulation parameters in the ODE model

Symbol Parameter (dimension) Default value (range*)
ρ Tumor growth rate (cells/day) 1 (0–7)
ξ Relative killing rate (cells/day) 0.001 (0–0.05)
h Michaelis constant (cells) 571
δ Death rate of immune cells (cells/day) 0.01958
α Conversion rate of naive T cells into specific T cells (cells/day) 0.0025
pS Total production rate of effector T cells from lymph nodes (cells/day) 1
mS Migration rate from lymph node to tumor microenvironment (cells/day) 1

*If not fixed.

ODE, ordinary differential equation.