Table 1:
Predictive significance of IFN Inducible Protein Score for subsequent serial FVC%
| MMF Arm* | |||
|---|---|---|---|
| Predictive significance of baseline IFN Score for serial FVC%s 3-12 months | |||
| Point estimate | 95% CI | p-value | |
| Baseline IFN Inducible Protein Score | 0.41 | 0.23 to 0.59 | 0.001 |
| Baseline FVC% | 0.84 | 0.82 to 0.86 | <0.001 |
| Predictive significance of 12-month IFN Score for serial FVC%s 15-24 months | |||
| Point estimate | 95% CI | p-value | |
| 12-month IFN Inducible Protein Score | 0.28 | 0.11 to 0.69 | 0.029 |
| 12-month FVC% | 0.96 | 0.9 to 0.98 | <0.001 |
| CYC Arm* | |||
| Predictive significance of baseline IFN Score for serial FVC%s 3-12 months | |||
| Point estimate | 95% CI | p-value | |
| Baseline IFN Inducible Protein Score | 0.91 | 0.56 to 1.13 | 0.009 |
| Baseline FVC% | 0.87 | 0.84 to 0.9 | <0.001 |
| Predictive significance of 12-month IFN Score for serial FVC%s 15-24 months | |||
| Point estimate | 95% CI | p-value | |
| 12-month IFN Inducible Protein Score | −0.61 | −1.5 to 0.11 | 0.068 |
| 12 month FVC% | 1 | 0.96 to 1.08 | <0.001 |
*
All models also included time as an independent variable