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. Author manuscript; available in PMC: 2022 Jun 1.
Published in final edited form as: Arthritis Rheumatol. 2021 May 2;73(6):997–1004. doi: 10.1002/art.41621

Table 4.

Rate Ratios for Risk of Prospective Thrombotic Events Based on Hydroxychloroquine Whole Blood Levels

RR (95% CI) p-value Adjusted RR (95% CI)1 Adjusted p-value1 Adjusted RR (95% CI)2 Adjusted p-value2
Mean HCQ blood level (per 200 ng/ml increase) 0.86 (0.75, 0.99) 0.030 0.87 (0.76, 1.00) 0.051 0.87 (0.76, 1.00) 0.056
Most recent HCQ blood level (per 200 ng/ml increase) 0.86 (0.77, 0.97) 0.013 0.87 (0.78, 0.98) 0.023 0.87 (0.78, 0.98) 0.025
1

Adjusted for age, ethnicity, and LAC

2

Adjusted for age, ethnicity, LAC, C3, and HTN

RR: Rate ratio; LAC: lupus anticoagulant; C3: complement component C3; HTN: arterial hypertension