Table 1:
Estimated Number of Persons with Systemic Lupus Erythematosus Living in the United States in 2018
| FEMALE | |||||
|---|---|---|---|---|---|
| Race/Ethnicity (Number of sites in analysis) |
SLE Prevalence a per 100,000 (95% CI) |
Population Denominator |
Estimated # SLE Cases in United States (95% CI) |
||
| Race | |||||
| Black (4) | 230.9 | (178.2, 299.2) | 24,880,722 | 57,450 | (44,337, 74,443) |
| White (4) | 84.7 | (68.4, 104.8) | 130,137,989 | 110,227 | (89,014, 136,437) |
| Asian/PI (3) | 84.4 | (48.3, 147.4) | 12,544,896 | 10,588 | (6,059, 18,491) |
| AI/AN (1) | 270.6 | (237.5, 307.0) | 2,238,966 | 6,059 | (5,318, 6,874) |
| Total b | 128.7 | (113.3, 146.2) | 169,802,573 | 184,323 | (144,729, 236,245) |
| Ethnicity | |||||
| Hispanic c (3) | 120.7 | (84.0, 173.4) | 30,689,083 | 37,042 | (25,779, 53,215) |
| MALE | |||||
| Prevalence a per 100,000 (95% CI) |
Population Denominator |
Estimated # SLE Cases in United States (95% CI) |
|||
| Race | |||||
| Black (4) | 26.7 | (19.6, 36.4) | 22,961,129 | 6,131 | (4,500, 8,358) |
| White (4) | 8.9 | (8.0, 10.1) | 127,942,583 | 11,387 | (10,235, 12,922) |
| Asian/PI (3) | 11.2 | (5.7, 21.9) | 11,660,533 | 1,306 | (665, 2,554) |
| AI/AN (1) | 53.8 | (36.2, 77.1) | 2,134,870 | 1,149 | (773, 1,646) |
| Total b | 14.6 | (12.2, 17.5) | 164,699,115 | 19,972 | (16,173, 25,480) |
| Ethnicity | |||||
| Hispanic c (3) | 18.0 | (15.6, 20.8) | 31,281,605 | 5,631 | (4,880, 6,507) |
Systemic lupus erythematosus cases were defined according to the 1997 revised American College of Rheumatology criteria.
Estimates for Blacks and whites are based on pooled estimates from the four state-based registries; Asian/Pacific Islanders (Asian/PI) and Hispanics are based on pooled estimates from Michigan, California and New York; American Indian/Alaska Native (AI/AN) estimates are based on the Indian Health Service Registry.
The pooled ‘total’ prevalence estimate includes Black, white and Asian/Pacific Islanders (Asian/PI). Since the American Indian/Alaska Native (AI/AN) prevalence was based on one registry and was significantly higher, it was not included in the pooled prevalence per 100,000.
Hispanic ethnicity is not mutually exclusive from the race categories, i.e., all Hispanic persons are included in one of the race categories. Thus, the pooled estimates do not incorporate the Hispanic rates since that would lead to duplicate counting. Estimates for Hispanics are based on pooled estimates from Michigan, California and New York.