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. Author manuscript; available in PMC: 2022 Jul 1.

Published in final edited form as: Exp Neurol. 2021 Mar 13;341:113694. doi: 10.1016/j.expneurol.2021.113694

Table.1.

Concentration of blood glucose, lipids, insulin and body weight

Feature	weeks	dm	db/db	db/db+exo-naïve	db/db+exo-146a
Body weight (g)	0	26.2±2.1	42.4±4.4^***	44.0±4.2	41.7±6.6
Body weight (g)	4	32.5±3.5	48.2±3.5^***	50.2±3.6	51.6±4.4
Blood glucose (mmol/l)	0	6.6±0.4	22.1±1.5^***	21.9±2.2	22.4±3.2
Blood glucose (mmol/l)	4	7.1±1.0	24.4±2.1^***	25.8±1.6	27.1±1.6
HbA_1c (%)	0	4.0±0.1	9.3±1.6^***	9.5±0.8	9.9±1.4
HbA_1c (%)	4	4.1±0.2	10.9±2.1^***	10.2±1.2	10.5±1.6
Total cholesterol (mmol/l)	0	2.0±0.3	3.6±0.4^***	3.5±0.4	3.7±0.2
Total cholesterol (mmol/l)	4	2.2±0.1	4.2±0.5^***	4.3±0.4	4.3±0.4
Triacylglycerol (mmol/l)	0	0.5±0.1	1.1±0.2^**	1.0±0.2	1.1±0.1
Triacylglycerol (mmol/l)	4	0.5±0.1	1.4±0.3^***	1.3±0.1	1.4±0.2
Serum Insulin (pmol/l)	0	118.0±15.5	266.0±26.0^***	259.0±21.2	267.0±25.5
Serum Insulin (pmol/l)	4	131.0±17.2	294.0±35.0^***	283.0±24.0	291.0±28.8

Values are mean ± SD.

^**

p<0.01,

^***

p<0.001 db/db vs dm. n= 8/group.