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. Author manuscript; available in PMC: 2022 Aug 1.
Published in final edited form as: Biochim Biophys Acta Mol Cell Biol Lipids. 2021 May 10;1866(8):158964. doi: 10.1016/j.bbalip.2021.158964

Figure 5. E-FABP coordinates FA responses in macrophages.

Figure 5

In E-FABP+ macrophages, E-FABP mediates multiple FA-induced responses, including FA oxidation and ROS production, inflammasome activation and IL-1β upregulation, lipid droplet formation and IFNβ responses, and nuclear transcriptional factor activation and gene regulation.