Table 1.
Baseline Characteristics of 23,981 women stratified by Major Osteoporotic fracture (MOF) and Hip fracture (HF) status.
| Subjects with MOF (n =1,637) | Subjects without MOF (n =22,281) | p Value | Subjects with HF (n=770) | Subjects without HF (n=23,148) | p Value | |
|---|---|---|---|---|---|---|
| Age (year), mean (SD) | 67.99 (±6.52) | 63.26 (±7.32) | <0.0001 | 69.48 (±5.71) | 63.39 (±7.34) | <0.0001 |
| Weight (kg), mean (SD) | 73.59 (±15.21) | 77.32 (±16.92) | <0.0001 | 72.42 (±15.28) | 77.22 (±16.86) | <0.0001 |
| Height (cm), mean (SD) | 161.25 (±6.30) | 161.06 (±6.29) | 0.28 | 161.8 (±6.27) | 161.1 (±6.29) | <0.01 |
| Body mass index (kg/m2), mean (SD) | 28.27 (±6.30) | 29.73 (±6.09) | <0.0001 | 27.61 (±5.44) | 29.69 (±6.07) | <0.0001 |
| Race/Ethnicity, n (%) | ||||||
| Whites | 1,255 (76.66) | 7,948 (35.67) | <.0001 | 600 (77.92) | 8,603 (37.17) | <.0001 |
| African American | 189 (11.55) | 9,231 (41.43) | 103 (13.38) | 9,317 (40.25) | ||
| Asian | 10 (0.61) | 467 (2.10) | 5 (0.65) | 472 (2.04) | ||
| Hispanic/Latino | 159 (9.71) | 4100 (18.40) | 51 (6.62) | 4,208 (18.18) | ||
| American Indian or Alaska Native | 24 (1.47) | 535 (2.40) | 11 (1.43) | 548 (2.37) | ||
| Smoking, n (%) | ||||||
| Never | 858 (52.42) | 11,704 (52.52) | 0.35 | 410 (53.25) | 12,152 (52.50) | 0.13 |
| Past | 639 (39.03) | 8,448 (37.92) | 303 (39.35) | 8,784 (37.95) | ||
| Current | 140 (8.55) | 2,129 (9.56) | 57 (7.40) | 2,212 (9.56) | ||
| ≥3 alcoholic drinks per day, n (%) | ||||||
| Yes | 24 (1.47) | 216 (0.97) | 0.05 | 10 (1.30) | 230 (0.99) | 0.40 |
| No | 1,613 (98.53) | 22,065 (99.03) | 760 (98.70) | 22,918 (99.01) | ||
| Rheumatoid arthritis, n (%) | ||||||
| Yes | 109 (6.66) | 1,500 (6.73) | 0.91 | 63 (8.18) | 1,546 (6.68) | 0.10 |
| No | 1,528 (93.34) | 20,781 (93.27) | 707 (91.82) | 21,602 (93.32) | ||
| Previous fragility fractures, n (%) | ||||||
| Yes | 835 (51.01) | 6,902 (30.98) | <0.0001 | 395 (51.30) | 7,342 (31.72) | <0.0001 |
| No | 802 (48.99) | 15,379 (95.04) | 375 (48.70) | 15,806 (68.28) | ||
| Familial history of hip fracture, n (%) | ||||||
| Yes | 271 (16.55) | 2,156 (9.68) | <0.0001 | 138 (17.92) | 2,289 (9.89) | <0.0001 |
| No | 1,366 (83.45) | 20,125 (93.64) | 632 (82.08) | 20,859 (90.11) | ||
| GRS_fracture, mean (SD) | 4.85 (±1.99) | 4.56 (±1.44) | <.0001 | 4.84 (±1.98) | 4.48 (±1.33) | <.0001 |
| GRS_BMD, mean (SD) | 4.30 (±0.40) | 4.00 (±0.45) | <.0001 | 4.29 (±0.39) | 4.01 (±0.45) | <.0001 |
| GRS_eBMD, mean (SD) | 27.19 (±0.77) | 26.56 (±0.87) | <0.0001 | 27.19 (±0.77) | 26.58 (±0.88) | <0.0001 |
*
Significant results are in boldface.