Skip to main content
. Author manuscript; available in PMC: 2022 Jun 1.
Published in final edited form as: Exp Physiol. 2021 May 14;106(6):1343–1358. doi: 10.1113/EP089449

Figure 1. Unpredictable chronic mild stress (UCMS) results in thoracic aortic perivascular adipose tissue impairment of aortic endothelial dependent dilation (EDD), which is prevented by aerobic exercise (AET) in both LZR and OZR rats.

Figure 1.

The impact of UCMS and UCMS+AET on EDD with and without tPVAT was tested by methacholine-induced relaxation of thoracic aortic rings using wire myograph in LZR (A&B) and OZR (C&D) groups. n=6–8 in each group or treatment. *denotes significant differences within treatments i.e., aortic ring with tPVAT relaxation compared to aortic ring with tPVAT relaxation or aortic ring only compared to aortic ring only. #denote significant effect of tPVAT, i.e., comparing aortic ring only to aortic ring with tPVAT. *p<0.05, **p<0.01, *** p<0.001, **** p<0.0001, #p<0.05, ##p<0.01 as measured by two-way repeated measures ANOVA with holm-sidak post-hoc analysis.