Table 1.

Animal Characteristics

	LZR			OZR
	Control	UCMS	UCMS+AET	Control	UCMS	UCMS+AET
Body Mass (g)	400±36	361±25*	343±21*	641±54	585±39*	567±46*
MAP (mmHg)	112±8	122±13	120±11	139±14	142±16	132±13
Glucose (mg/dl)	98±15	124±17	115±15	184±29	230±34	219±36
TG (mg/dl)	25±7	54±40	36±8	124±19	114±35	103±40
Corticosterone (ng/ml)	7.0±0.4	8.8±1.7*	10.7±4	13.8±1.4	17.3±5.2*	15.8±4.0*
Coat Score (AU)	0.6±0.4	1.5±0.4*	1.8±0.8*	2.4±0.4	4.8±0.8*	4.5±0.4*
Adrenal weight (mg)	16.8±2.3	25.2±4.2*	21.4±3.1*	27.2±3.9	32.7±6.5	32.0±6.7
Normalized adrenal weight (mg/g)	0.040±0.003	0.068±0.008*	0.063±0.006*	0.045±0.006	0.056±0.008*	0.061±0.008*
Aorta Wall Thickness (μm)	120±16	116±14	119±17	138±11	141±16	118±8*

Data represented as Mean ± SD,

^*denotes statistical difference compared to with specie control (i.e., LZR or OZR) measured by ANOVA with Holm-Sidak Post-Hoc p<0.05 (n=6–8).

MAP, mean arterial pressure; TG, triglyceride. p=0.06 for glucose and MAP in LZR con vs UCMS; p=0.06 glucose OZR con vs UCMS.