Skip to main content
. Author manuscript; available in PMC: 2022 Jun 1.
Published in final edited form as: Curr Opin Microbiol. 2021 Apr 18;61:91–98. doi: 10.1016/j.mib.2021.03.005

Figure 4.

Figure 4.

DEAD box proteins regulate the assembly and turnover of condensates. (a) DEAD box proteins undergo oligomerization in the presence of RNA and ATP forming RNP condensates. These RNP condensates may organize various RNA processing reactions depending on the function of a DEAD box ATPase. Upon the stimulation of ATPase activity by a regulatory protein, RNA is released leading to the dissolution of condensate [55]. (b) DEAD box proteins can act as chaperones by reducing the multivalent interactions between RNA molecules in the condensate by means of its ATPase activity. This activity of DEAD box proteins potentially reduces RNA/RNP condensation in the cytoplasm of cells [56].