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. Author manuscript; available in PMC: 2022 May 1.
Published in final edited form as: Immunobiology. 2021 Apr 6;226(3):152089. doi: 10.1016/j.imbio.2021.152089

Figure 2. IR-induced effects on levels of cleaved caspase-3 and phosphorylated p53 in RAG2-expressing cells.

Figure 2.

(A) Detection of caspase-3 cleavage in cells that expressed either FL or T490A. The samples were prepared at the indicated times following IR. In (B) is plotted the averaged ratio of caspase-3 cleavage measured in treated and untreated samples at each time point. The error bars represent SD (n=3). (C) Detection of p53 phosphorylation following IR in cells that expressed either FL or T490A. In (D) is the averaged ratio of p53 phosphorylation in treated and untreated cells measured at the indicated time points following IR. The error bars represent SD (n=3). *, p<0.05 by student’s t test