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Body weight (bw) for A) male and D) female pups dosed with Al2O3 NP (dotted line) and vehicle control (solid line) between PND 17–20. Pups were sacrificed on PDN 21, and the liver-to-bw ratio for B) male and E) female and brain-to-bw ratio for C) male and F) female pups were calculated. In male pups Al2O3 NP administration caused a significant increase in liver-to-bw ratio. The graphs show mean ± standard deviation.
