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. 2021 Apr 30;18(3):327–341. doi: 10.1007/s13770-021-00333-4

Table 1.

The main characteristics of various bone grafts [34]

Graft Definition Advantages Disadvantages Examples
Autogenous bone The patient’s own bone Excellent biocompatibility, bone conductivity, and bone induction and contains living osteoblasts [17] Needs additional surgery, which can cause complications such as nerve damage or arterial injury [22] Cortical or cancellous bone
Allogeneic bone A graft taken from a genetically dissimilar member of the same species as the recipient Has various tissue cells, growth factors, extracellular matrix, and other factors [26] Antigenic and low risk of spreading disease Cadaver cortical or cancellous bone, FDBA, DFDBA
Xenogeneic bone Grafts derived from a genetically different species than the recipient High volume, and some grafts have excellent bone conductivity Highly antigenic and high risk of spreading disease Bio-Oss, coralline HA, red algae
Alloplastic (synthetic materials) bone Fabricated graft materials Can be manufactured and stored in large quantities Causes inflammation and poor bone induction [116] Calcium sulfate, bioactive glass, HA, NiTi

FDBA freeze-dried bone allograft, DFDBA demineralized freeze-dried bone allograft; HA hydroxyapatite